49ers -3 total 49 as the playoff push has started early in a couple of places and both these teams need this for playoff positioning. 9 of 10 games have been single possession games for Minnesota, they have not lost a game by multiple scores this year. They got the come from behind at home against Green Bay which common opponent SF lost by a late field goal to GB. The Vikings have won 4 of 6 games now.
San Fran has lost 12 of 15 home games with only home wins coming against the Rams. Jimmy G has a 100+ passer rating in his last 4 games, and they bring the 3rd ranked defense along.
San Francisco allowing 22.2 per game, Minnesota 24.2. The 49ers scoring 24.6 per game, the Vikings 25.2.
My Prediction 24-22 49ers.