The NFL season kicks off in the same stadium where it ended with the Rams winning the Super Bowl on their home field. Its currently pk -110 with the Total at 52. Last year the Bills averaged 31.2 per game, while allowing a league best 17 per game. The Rams scored 27.1 per contest while allowing 21.9. The side play here could go either way the Bills +600 to win the Super Bowl as they have added Von Miller from the Rams to their own defense. The Rams +1100 to repeat as champs. Last time they met in Orchard Park NY was 2020, the Rams of course had Jared Goff at QB then. It was the Bills up 21-3 at half before the Rams comeback fell short 35-32. Even though both these teams have great defenses as the stats from last year show they also bring in two of the best offenses. Last year these teams were 18th and 19th in the league in percent of run plays per game at just over 40% of the time.
This thing could go either way obviously, my prediction Bills 31 Rams 28. My pick here is the Bills -2.5 and OVER 52.